Recombinant Transcription Factor 7 Like 2 Monoclonal Antibody
Product Sizes
50 ul
£265.00
RD86960A-50UL
100 ul
£399.00
RD86960A-100UL
About this Product
- SKU:
- RD86960A
- Additional Names:
- TCF7L2,HMG box transcription factor 4,HTCF-4,T-cell factor-4 variant X2,T-cell factor 4,Transcription factor 7-like 2,TCF-4
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- 50mm tris-glycine
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small inTine.|This is a Recombinant Transcription Factor 7 Like 2 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human TCF-4
- Isotype:
- IgG
- Molecular Weight:
- 16kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:recombinant-transcription-factor-7-like-2-monoclonal-antibody-29826.html
