Recombinant Caspase 3 Monoclonal Antibody
Product Sizes
50 ul
£265.00
RD86917A-50UL
100 ul
£399.00
RD86917A-100UL
About this Product
- SKU:
- RD86917A
- Additional Names:
- A830040C14Rik,Apopain,CASP-3,CASP3,CASP3,Casp3a,Caspase 3,Caspase 3,apoptosis-related cysteine peptidase,Caspase 3,apoptosis-related cysteine protease,Caspase 3,apoptosis-related cysteine protease a,Caspase-3 subunit p12,CC3,CPP-32,CPP32,CPP32B,Cysteine p
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- 50mm tris-glycine
- Clonality:
- Monoclonal
- Concentration:
- 300 ug/ml
- Extra Details:
- Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs MW of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3.|This is a Recombinant Caspase 3 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human Caspase 3
- Isotype:
- IgG
- Molecular Weight:
- 86kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:recombinant-caspase-3-monoclonal-antibody-29801.html
