PABPN1 Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD83614A-60UL
120 ul
£479.00
RD83614A-120UL
200 ul
£761.00
RD83614A-200UL
About this Product
- SKU:
- RD83614A
- Additional Names:
- PABPN1,OPMD,PAB2,PABII,PABP-2,PABP2
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.|This is a PABPN1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human PABPN1 (NP_004634.1).
- Isotype:
- IgG
- Molecular Weight:
- 45 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:pabpn1-polyclonal-antibody-13848.html
