ABL1 Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD80028A-60UL
120 ul
£479.00
RD80028A-120UL
200 ul
£761.00
RD80028A-200UL
About this Product
- SKU:
- RD80028A
- Additional Names:
- ABL,JTK7,p150,c-ABL,v-abl,CHDSKM,c-ABL1,ABL1,c-Abl,bcr/abl
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons.|This is a ABL1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human ABL1 (NP_005148.2).
- Isotype:
- IgG
- Molecular Weight:
- 139 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:abl1-polyclonal-antibody-11710.html
