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Antibodies

CAB39 Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD79153A-20UL
60 ul
£242.00
RD79153A-60UL
120 ul
£372.00
RD79153A-120UL
200 ul
£585.00
RD79153A-200UL
About this Product
SKU:
RD79153A
Additional Names:
Cab39,CAB39,Calcium binding protein 39,Calcium-binding protein 39,CGI 66,CGI-66,CGI66,MO25 alpha,MO25,Mouse protein 25 alpha,Protein Mo25
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).|This is a CAB39 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CAB39
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody