NUAK1 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD78846A-20UL
60 ul
£242.00
RD78846A-60UL
120 ul
£372.00
RD78846A-120UL
200 ul
£585.00
RD78846A-200UL
About this Product
- SKU:
- RD78846A
- Additional Names:
- AMP activated protein kinase family member 5,AMPK related protein kinase 5,AMPK-related protein kinase 5,NUAK family SNF1 like kinase,NUAK family SNF1-like kinase 1,Nuak1,NUAK1,Omphalocele kinase 1,Probable serine/threonine protein kinase KIAA0537
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.4 mg/ml
- Extra Details:
- NUAK family SNF1-like kinase 1also known asAMPK-related protein kinase 5(ARK5) is anenzymethat in humans is encoded by theNUAK1gene. Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression. Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53. Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability. Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex. Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.|This is a NUAK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human NUAK1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:nuak1-polyclonal-antibody-11076.html
