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Antibodies

DCC Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD78669A-20UL
60 ul
£242.00
RD78669A-60UL
120 ul
£372.00
RD78669A-120UL
200 ul
£585.00
RD78669A-200UL
About this Product
SKU:
RD78669A
Additional Names:
Colorectal cancer related chromosome sequence 18,Colorectal cancer suppressor,CRC 18,CRC18,CRCR 1,CRCR1,DCC,DCC,Deleted in colorectal cancer protein,Deleted in colorectal carcinoma,Immunoglobulin superfamily DCC subclass member 1,Netrin receptor DCC,Tumor
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.|This is a DCC Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human DCC
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody