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Antibodies

SPAG1 Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD78641A-20UL
60 ul
£242.00
RD78641A-60UL
120 ul
£372.00
RD78641A-120UL
200 ul
£585.00
RD78641A-200UL
About this Product
SKU:
RD78641A
Additional Names:
CILD28,FLJ32920,HSD-3.8,Infertility related sperm protein Spag 1,SP75,SPAG1,Sperm associated antigen 1,Tetratricopeptide repeat-containing protein,TPIS,TPR containing protein involved in spermatogenesis
Application:
ELISA, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.3 mg/ml
Extra Details:
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.|This is a SPAG1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human SPAG1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody