DAB2 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD78002A-20UL
60 ul
£242.00
RD78002A-60UL
120 ul
£372.00
RD78002A-120UL
200 ul
£585.00
RD78002A-200UL
About this Product
- SKU:
- RD78002A
- Additional Names:
- DAB 2,Dab,mitogen-responsive phosphoprotein,homolog 2 (Drosophila),DAB2,Differentially expressed in ovarian cancer 2,Differentially expressed protein 2,Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein),Disabled homolog 2,Disabled homolog
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.|This is a DAB2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DAB2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:dab2-polyclonal-antibody-10485.html
