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Antibodies

FADD Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD77415A-20UL
60 ul
£242.00
RD77415A-60UL
120 ul
£372.00
RD77415A-120UL
200 ul
£585.00
RD77415A-200UL
About this Product
SKU:
RD77415A
Additional Names:
FADD,FADD protein,FADD,Fas (TNFRSF6) associated via death domain,Fas associated via death domain,Fas associating death domain containing protein,Fas associating protein,Fas associating protein with death domain,Fas TNFRSF6 associated via death domain,FAS
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.|This is a FADD Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant protein of human FADD
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody