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Antibodies

HIF1AN Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD77085A-20UL
60 ul
£242.00
RD77085A-60UL
120 ul
£372.00
RD77085A-120UL
200 ul
£585.00
RD77085A-200UL
About this Product
SKU:
RD77085A
Additional Names:
DKFZp762F1811,Factor inhibiting HIF-1,Factor inhibiting HIF1,FIH 1,FIH-1,FIH1,FLJ20615,FLJ22027 ,HIF1AN,HIF1N,Hypoxia inducible factor 1 alpha inhibitor,Hypoxia inducible factor 1 alpha subunit inhibitor,Hypoxia inducible factor asparagine hydroxylase,Hyp
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.|This is a HIF1AN Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human HIF1AN
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody