CBL Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD76740A-20UL
60 ul
£242.00
RD76740A-60UL
120 ul
£372.00
RD76740A-120UL
200 ul
£585.00
RD76740A-200UL
About this Product
- SKU:
- RD76740A
- Additional Names:
- 4732447J05Rik,C CBL,Cas Br M (murine) ecotropic retroviral transforming sequence,Casitas B lineage lymphoma proto oncogene,Casitas B-lineage lymphoma proto-oncogene,CBL 2,cbl,CBL,CBL2,E3 ubiquitin protein ligase CBL,E3 ubiquitin-protein ligase CBL,Oncogen
- Application:
- ELISA, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.4 mg/ml
- Extra Details:
- This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder|This is a CBL Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human CBL
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:cbl-polyclonal-antibody-9674.html
