SRGAP3 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD76121A-20UL
60 ul
£242.00
RD76121A-60UL
120 ul
£372.00
RD76121A-120UL
200 ul
£585.00
RD76121A-200UL
About this Product
- SKU:
- RD76121A
- Additional Names:
- ARHGAP 14,ARHGAP14,Gbi,ME GAP,MEGAP,Mental disorder associated GAP,Mental disorder-associated GAP,Rho GTPase activating protein 14,Rho GTPase-activating protein 14,SLIT ROBO Rho GTPase activating protein 3,SLIT-ROBO Rho GTPase-activating protein 3,srGAP 2
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- SRGAP3 is a 1099 amino acid protein containing 1 FCH domain, 1 Rho-GAP domain and 1 SH3 domain. Expressed highly in brain, and in lower levels in kidney, WRP is thought to play a role in cell migration through its interaction with Cdc42 and Rac1. Cdc42 and Rac1 are two intracellular signaling proteins that regulate the multistep cell migration process. WRP downregulates Cdc42 and Rac1 activity, thereby impairing actin and microtubule dynamics, the formation of protrusions, and total cell migration. Defects in the gene encoding WRP have been linked to severe idiopathic mental retardation. Three isoforms of WRP exist as a result of alternative splicing events.|This is a SRGAP3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human SRGAP3
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:srgap3-polyclonal-antibody-9246.html
