DDIT4 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD75767A-20UL
60 ul
£242.00
RD75767A-60UL
120 ul
£372.00
RD75767A-120UL
200 ul
£585.00
RD75767A-200UL
About this Product
- SKU:
- RD75767A
- Additional Names:
- DDIT4,DDIT4,Dig2,DNA damage inducible transcript 4,DNA damage inducible transcript 4 protein,DNA damage-inducible transcript 4 protein,FLJ20500,HIF 1 responsive protein RTP801,HIF 1 responsive RTP801,HIF-1 responsive protein RTP801,Protein regulated in de
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- REDD-1, also designated DNA-damage-inducible transcript 4, dig2 or RTP801, is thought to function in the regulation of reactive oxygen species (ROS). REDD-1 expression has also been linked to apoptosis, Ab toxicity and the pathogenesis of ischemic diseases. As an HIF-1-responsive gene, REDD-1 exhibits strong hypoxia-dependent upregulation in ischemic cells of neuronal origin. In response to stress due to DNA damage and glucocorticoid treatment, REDD-1 is upregulated at the transcriptional level. REDD-1 negatively regulates the mammalian target of Rapamycin (mTOR), a serine/threonine kinase often referred to as FRAP. It is crucial in the coupling of extra- and intracellular cues to FRAP regulation. The absence of REDD-1 is associated with the development of retinopathy, a major cause of blindness.|This is a DDIT4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human DDIT4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ddit4-polyclonal-antibody-9012.html
