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Antibodies

MDM2 Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD71433A-20UL
60 ul
£242.00
RD71433A-60UL
120 ul
£372.00
RD71433A-120UL
200 ul
£585.00
RD71433A-200UL
About this Product
SKU:
RD71433A
Additional Names:
ACTFS,Double minute 2 protein,E3 ubiquitin-protein ligase Mdm2,Hdm 2,Hdm2,HDMX,MDM 2,MDM2,MDM2 oncogene E3 ubiquitin protein ligase,Mdm2 p53 E3 ubiquitin protein ligase homolog,Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding
Application:
ELISA, IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.|This is a MDM2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human MDM2 around the non-phosphorylation site of Ser166.
Isotype:
IgG
Molecular Weight:
90 kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Non-human Primate
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody