P62/SQSTM1 Polyclonal Antibody
Product Sizes
60 ul
£265.00
RD70522A-60UL
120 ul
£399.00
RD70522A-120UL
200 ul
£600.00
RD70522A-200UL
About this Product
- SKU:
- RD70522A
- Additional Names:
- A170,DMRV,EBI 3 associated protein of 60 kDa,EBI 3 associated protein p60,EBI3 associated protein of 60 kDa,EBI3 associated protein p60,EBI3-associated protein of 60 kDa,EBIAP,FTDALS3,MGC127197,ORCA,OSF-6,Osi,OSIL,Oxidative stress induced like,p60,p62,p62
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.58 mg/ml
- Extra Details:
- Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFK KappaB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.|This is a P62/SQSTM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse P62
- Isotype:
- IgG
- Molecular Weight:
- 62 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p62-sqstm1-polyclonal-antibody-8298.html
