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Antibodies

PKM Polyclonal Antibody

Product Sizes
60 ul
£265.00
RD70474A-60UL
120 ul
£399.00
RD70474A-120UL
200 ul
£600.00
RD70474A-200UL
About this Product
SKU:
RD70474A
Additional Names:
CTHBP,Cytosolic thyroid hormone binding protein,Cytosolic thyroid hormone-binding protein,KPYM,MGC3932,OIP 3,OIP-3,OIP3,OPA interacting protein 3,Opa-interacting protein 3,p58,PK muscle type,PK,muscle type,PK2,PK3,PKM,PKM2,pykm,Pyruvate kinase 2/3,Pyruvat
Application:
Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
440 ug/ml
Extra Details:
PKM2,also named as OIP3,PK2,PK3,PKM,p58,THBP1,CTHBP and Tumor M2-PK,belongs to the pyruvate kinase family. It is glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP,generating ATP. It stimulates POU5F1-mediated transcriptional activation. PKM2 plays a general role in caspase independent cell death of tumor cells. The activity of the M2 isoform (but not the M1 isoform) can be inhibited by tyrosine kinase signalling in tumourcells.The primary pyruvate kinase isoform before tumour development is PK-M1; however,the primary isoform from four independent tumours is PK-M2. PKM2,Pyruvate kinase isozymes M1/M2,has 2 isoforms .The immunogen of this antibody is M2 isoform,also called PKM2.|This is a PKM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant protein corresponding to Mouse PKM2
Isotype:
IgG
Molecular Weight:
58 kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody