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Antibodies

E-Cadherin Monoclonal Antibody

Product Sizes
60 ul
£265.00
RD70450A-60UL
120 ul
£399.00
RD70450A-120UL
200 ul
£600.00
RD70450A-200UL
About this Product
SKU:
RD70450A
Additional Names:
Arc 1,CADH1,Cadherin 1,cadherin 1 type 1 E-cadherin,Cadherin1,CAM 120/80,CD 324,CD324,CD324 antigen,cdh1,CDHE,E-Cad/CTF3,E-cadherin,ECAD,Epithelial cadherin,epithelial calcium dependant adhesion protein,LCAM,Liver cell adhesion molecule,UVO,Uvomorulin
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Monoclonal
Concentration:
1.6 mg/ml
Extra Details:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.|This is a E-Cadherin Monoclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Immunogen:
Recombinant protein corresponding to MouseE-cadherin
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody