FOXO1 Polyclonal Antibody
Product Sizes
60 ul
£265.00
RD70350A-60UL
120 ul
£399.00
RD70350A-120UL
200 ul
£600.00
RD70350A-200UL
About this Product
- SKU:
- RD70350A
- Additional Names:
- FKH 1,FKH1,FKHR,Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma),Forkhead box O1,Forkhead box protein O1,Forkhead box protein O1A,Forkhead in rhabdomyosarcoma,Forkhead,Drosophila,homolog of,in rhabdomyosarcoma,FoxO transcription factor,foxo1,FOXO1,FOXO1
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.58 mg/ml
- Extra Details:
- FOXO1,also named as FOXO1A,FKHR and FKH1,is a member of the FOXO subfamily of Forkhead transcription factors. FOXO1 is a transcription factor which acts as a regulator of cell responses to oxidative stress. FOXO1 interacts with LRPPRC and SIRT1. In the presence of KIRT1,FOXO1 mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. FOXO1 contains three predicted protein kinase B phosphorylation sites (Thr-24,Ser-256,and Ser-319) that are conserved in other FOXO proteins. The t(2;13) and the variant t(1;13) translocations generate PAX3/FKHR and PAX7/FKHR fusion proteins respectively. The resulting protein is a transcriptional activator. Defects in FOXO1 are a cause of rhabdomyosarcoma type 2 (RMS2).|This is a FOXO1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to Mouse FOXO1
- Isotype:
- IgG
- Molecular Weight:
- 78 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:foxo1-polyclonal-antibody-8133.html
