BRCA2 Polyclonal Antibody
Product Sizes
20 ul
£138.00
RD70171A-20UL
60 ul
£218.00
RD70171A-60UL
120 ul
£359.00
RD70171A-120UL
200 ul
£560.00
RD70171A-200UL
About this Product
- SKU:
- RD70171A
- Additional Names:
- BRCA 2, BRCC 2, Breast and ovarian cancer susceptibility gene early onset antibody, BROVCA2, FACD, FAD 1, FANCB, GLM3
- Application:
- Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.|This is a BRCA2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Breast cancer type 2 susceptibility protein
- Isotype:
- IgG
- Molecular Weight:
- 384 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:brca2-polyclonal-antibody-7972.html
