AF488 Anti-Human CD192/CCR2 Antibody[K036C2]
Product Sizes
20 tests
£185.00
RD30856F-20TESTS
100 tests
£399.00
RD30856F-100TESTS
2 x 100 tests
£573.00
RD30856F-2X100TESTS
About this Product
- SKU:
- RD30856F
- Additional Names:
- CKR2,CCR2A,CCR2B,CKR2A,CKR2B,CMKBR2,MCP-1-R,CC-CKR-2
- Application:
- Flow Cytometry
- Buffer:
- PBS
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 488
- Concentration:
- 5 ul/test
- Extra Details:
- CCR2 is a chemokine receptor that binds monocyte chemoattractant proteins (MCP-1, 2, 3 and 4). Two spliced variants were initially described for CCR2 (CCR2A and CCR2B). These variants differ in their terminal carboxyl tails. Monocyte adhesion to the arterial endothelium and subsequent migration into the intima are central events in the pathogenesis of atherosclerosis. CCR2 and MCP-1 have been associated to atherosclerotic plaques. MCP-1 is induced by modified-LDL in endothelial cells and may trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Local overexpression of MCP-1 at vessel walls induces infiltration of macrophages and formation of atherosclerotic lesions. Obesity induces an inflammatory state that is implicated in many clinically important complications, including insulin resistance, diabetes, atherosclerosis, and non-alcoholic fatty liver disease. CCR2 influences the development of obesity and associated adipose tissue inflammation.|This is a AF488 Anti-Human CD192/CCR2 [K036C2] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotype:
- IgG2a, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:af488-anti-human-cd192-ccr2-antibody-k036c2--33514.html
