APC Anti-Mouse/Rat Foxp3 Antibody[FJK-16s]

Product Sizes

25 ug

£238.00

RD30833F-25UG

100 ug

£453.00

RD30833F-100UG

About this Product

SKU:: RD30833F
Additional Names:: Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
Application:: Flow Cytometry, Immunocytochemistry
Buffer:: PBS
Clonality:: Monoclonal
Conjugate:: APC
Concentration:: 0.2 mg/ml
Extra Details:: FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.|This is a APC Anti-Mouse/Rat Foxp3 [FJK-16s] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:: Rat
Isotype:: IgG2a, kappa
Reactivities:: Mouse, Rat
Shipping Conditions:: Blue Ice
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Reddot
Type:: Antibody: Monoclonal Antibody

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