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Antibodies

Purified Anti-Human CD8a Antibody[HIT8a]

Product Sizes
25 ug
£83.00
RD30661F-25UG
100 ug
£158.00
RD30661F-100UG
About this Product
SKU:
RD30661F
Additional Names:
T-cell surface glycoprotein CD8 alpha chain,CD8A,T8,Leu2,MAL
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
HIT8a
Clonality:
Monoclonal
Concentration:
0.5 mg/ml
Extra Details:
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3?domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.|This is a Purified Anti-Human CD8a [HIT8a] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Isotype:
IgG1, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Reddot
Type:
Antibody