AF647 Anti-Human CD196/CCR6 Antibody[G034E3]
Product Sizes
20 tests
RD30611F-20TESTS
100 tests
RD30611F-100TESTS
2 x 100 tests
RD30611F-2X100TESTS
About this Product
- SKU:
- RD30611F
- Additional Names:
- CKRL3, CMKBR6, GPR29, STRL22,GPRCY4
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- G034E3
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 647
- Concentration:
- 5 ul/test
- Extra Details:
- CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the B Beta defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.|This is a AF647 Anti-Human CD196/CCR6 [G034E3] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotype:
- IgG2b, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Reddot
- Type:
- Antibody
- Manufacturer's Data Sheet:af647-anti-human-cd196-ccr6-antibody-g034e3--33293.html
