AFViolet 450 Anti-Mouse CD22 Antibody[Cy34.1]
Product Sizes
25 ug
RD30584F-25UG
100 ug
RD30584F-100UG
About this Product
- SKU:
- RD30584F
- Additional Names:
- B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- Cy34.1
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 450
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig u chain are augmented in the presence of Cy34.1 mAb.|This is a AFViolet 450 Anti-Mouse CD22 [Cy34.1] Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Reddot
- Type:
- Antibody
- Manufacturer's Data Sheet:afviolet-450-anti-mouse-cd22-antibody-cy34-1--33274.html
