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Antibodies

PXR Polyclonal Antibody

Product Sizes
60 ul
£319.00
RD267027A-60UL
120 ul
£479.00
RD267027A-120UL
200 ul
£761.00
RD267027A-200UL
About this Product
SKU:
RD267027A
Additional Names:
NR1I2,BXR,ONR1,PAR,PAR1,PAR2,PARq,PRR,PXR,SAR,SXR
Application:
Immunofluorescence, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.|This is a PXR Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Recombinant protein of human PXR
Isotype:
IgG
Molecular Weight:
50 kDa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody