VHL Polyclonal Antibody
Product Sizes
60 ul
£319.00
RD266748A-60UL
120 ul
£479.00
RD266748A-120UL
200 ul
£761.00
RD266748A-200UL
About this Product
- SKU:
- RD266748A
- Additional Names:
- VHL,HRCA1,RCA1,VHL1,pVHL,PVHL
- Application:
- Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This is a VHL Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.|Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of human VHL (NP_937799.1).
- Isotype:
- IgG
- Molecular Weight:
- 24 kDa
- Purification:
- Affinity Purified
- Reactivities:
- Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:vhl-polyclonal-antibody-6069.html
