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Antibodies

ITGA8 Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD253512A-20UL
60 ul
£242.00
RD253512A-60UL
120 ul
£372.00
RD253512A-120UL
200 ul
£585.00
RD253512A-200UL
About this Product
SKU:
RD253512A
Additional Names:
Integrin alpha 8,Integrin alpha-8 heavy chain,Integrin alpha-8 light chain,ITA8,ITGA 8,ITGA8
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.|This is a ITGA8 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human ITGA8
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody