SRPK2 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD253007A-20UL
60 ul
£242.00
RD253007A-60UL
120 ul
£372.00
RD253007A-120UL
200 ul
£585.00
RD253007A-200UL
About this Product
- SKU:
- RD253007A
- Additional Names:
- Human serine kinase SRPK2 mRNA, complete cds,Serine kinase SRPK2,Serine/arginine rich protein specific kinase 2,Serine/arginine-rich protein-specific kinase 2,Serine/threonine protein kinase SRPK2 ,SFRS protein kinase 2,SFRSK2 ,SR protein specific kinase
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.96 mg/ml
- Extra Details:
- Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28. Can mediate hepatitis B virus (HBV) core protein phosphorylation. Plays a negative role in the regulation of HBV replication through a mechanism not involving the phosphorylation of the core protein but by reducing the packaging efficiency of the pregenomic RNA (pgRNA) without affecting the formation of the viral core particles.|This is a SRPK2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human SRPK2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:srpk2-polyclonal-antibody-4674.html
