CBFA2T2 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD252991A-20UL
60 ul
£242.00
RD252991A-60UL
120 ul
£372.00
RD252991A-120UL
200 ul
£585.00
RD252991A-200UL
About this Product
- SKU:
- RD252991A
- Additional Names:
- AML1 MTG8,cbfa2t2,Core binding factor runt domain alpha subunit 2 translocated to 2,core-binding factor, runt domain, alpha subunit 2,DKFZp313F2116,EHT,ETO homolog on chromosome 20,ETO homologous on chromosome 20,MTG 8 like protein,MTG 8 related protein 1
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.08 mg/ml
- Extra Details:
- In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.|This is a CBFA2T2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human CBFA2T2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:cbfa2t2-polyclonal-antibody-4658.html
