NR0B2 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD252169A-20UL
60 ul
£242.00
RD252169A-60UL
120 ul
£372.00
RD252169A-120UL
200 ul
£585.00
RD252169A-200UL
About this Product
- SKU:
- RD252169A
- Additional Names:
- NR0B2,NR0B2,Nr0b2a,Nuclear receptor subfamily 0 group B member 2,Nuclear receptor subfamily 0, group B, member 2a,Orphan nuclear receptor SHP,SHP,SHP-1,Shp1,Small heterodimer partner
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.|This is a NR0B2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human NR0B2
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:nr0b2-polyclonal-antibody-4049.html
