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Antibodies

RBL2 Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD219324A-20UL
60 ul
£242.00
RD219324A-60UL
120 ul
£372.00
RD219324A-120UL
200 ul
£585.00
RD219324A-200UL
About this Product
SKU:
RD219324A
Additional Names:
130 kDa retinoblastoma associated protein,130 kDa retinoblastoma-associated protein,IB4,p130,PPAR-alpha-interacting complex protein 128,PRB2,Rb2,Rbl2,RBL2,RBR 2,RBR-2,RBR2,Retinoblastoma like 2,Retinoblastoma-like protein 2,Retinoblastoma-related protein
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.8 mg/ml
Extra Details:
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.|This is a RBL2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human RBL2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody