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Antibodies

CUL4A Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD219279A-20UL
60 ul
£242.00
RD219279A-60UL
120 ul
£372.00
RD219279A-120UL
200 ul
£585.00
RD219279A-200UL
About this Product
SKU:
RD219279A
Additional Names:
2810470J21Rik,AW495282,CUL 4A,CUL-4A,Cul4a,Cul4a protein,CUL4A,Cullin-4A,MGC36573,MGC64071
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1.62 mg/ml
Extra Details:
Cullin proteins assemble a large number of RING E3 ubiquitin ligases,participating in the proteolysis through the ubiquitin-proteasome pathway. Two cullin 4 (CUL4) proteins,CUL4A (87 kDa) and CUL4B(104 kDa),have been identified. The two CUL4 sequences are 83% identical. They target certain proteins for degradation by binding protein DDB1 to form a CUL4-DDB1 ubiquitin ligase complex with DDB. They form two individual E3 ligases,DDB1-CUL4ADDB2 and DDB1-CUL4BDDB2 in this process. CUL4A appeared in both the nucleus and the cytosol,suggesting a more complex mechanism for entering the nucleus. CUL4B is localized in the nucleus and facilitates the transfer of DDB1 into the nucleus independently of DDB2.|This is a CUL4A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Synthetic peptide of human CUL4A
Isotype:
IgG
Molecular Weight:
Refer to figures
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody