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Antibodies

LIG4 Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD218863A-20UL
60 ul
£242.00
RD218863A-60UL
120 ul
£372.00
RD218863A-120UL
200 ul
£585.00
RD218863A-200UL
About this Product
SKU:
RD218863A
Additional Names:
DNA ligase IV ATP dependent,DNA joinase,DNA ligase 4,DNA ligase IV,DNA repair enzyme,DNLI4,LIG 4,LIG4,LIG4S,Ligase IV,Ligase IV DNA ATP dependent,Polydeoxyribonucleotide synthase [ATP] 4,Polydeoxyribonucleotide synthase 4,Polydeoxyribonucleotide synthase
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.72 mg/ml
Extra Details:
The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. Alternatively spliced transcript variants encoding the same protein have been observed.|This is a LIG4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Fusion protein of human LIG4
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody