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Antibodies

TPMT Polyclonal Antibody

Product Sizes
20 ul
£148.00
RD218800A-20UL
60 ul
£242.00
RD218800A-60UL
120 ul
£372.00
RD218800A-120UL
200 ul
£585.00
RD218800A-200UL
About this Product
SKU:
RD218800A
Additional Names:
HGNC:12014,S adenosyl L methionine thiopurine S methyltransferase,Thiopurine methyltransferase,Thiopurine S methyltransferase,Thiopurine S-methyltransferase,TPMT,TPMT
Application:
ELISA, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.96 mg/ml
Extra Details:
This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.|This is a TPMT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rabbit
Immunogen:
Fusion protein of human TPMT
Isotype:
IgG
Molecular Weight:
Refer to figures
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Reddot
Type:
Antibody: Polyclonal Antibody