IMPA1 Polyclonal Antibody
Product Sizes
20 ul
£148.00
RD218668A-20UL
60 ul
£242.00
RD218668A-60UL
120 ul
£372.00
RD218668A-120UL
200 ul
£585.00
RD218668A-200UL
About this Product
- SKU:
- RD218668A
- Additional Names:
- IMP 1,IMP,IMPA 1,IMPA,IMPA1,IMPA1,IMPase 1,IMPase,Inositol 1(or 4) monophosphatase,Inositol monophosphatase 1,Inositol monophosphatase,Inositol(myo) 1(or 4) monophosphatase 1,Inositol-1(or 4)-monophosphatase 1,Lithium sensitive myo inositol monophosphatas
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.|This is a IMPA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human IMPA1
- Isotype:
- IgG
- Molecular Weight:
- Refer to figures
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Reddot
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:impa1-polyclonal-antibody-2128.html
