AF647 Anti-Human CD197/CCR7 Antibody
Product Sizes
20 tests
RD21855F-20TESTS
100 tests
RD21855F-100TESTS
2 x 100 tests
RD21855F-2X100TESTS
About this Product
- SKU:
- RD21855F
- Additional Names:
- CMKBR7, EBI1, EVI1,CCR-7,CDw197
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- G043H7
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 647
- Extra Details:
- CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B cells recirculate between B-cell-rich compartments (follicles or B cell zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis. Product Details|This is a AF647 Anti-Human CD197/CCR7 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotype:
- IgG2a, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:af647-anti-human-cd197-ccr7-antibody-2063.html
