AF647 Anti-Human CD49d Antibody
Product Sizes
20 tests
£191.00
RD21767F-20TESTS
100 tests
£412.00
RD21767F-100TESTS
2 x 100 tests
£630.00
RD21767F-2X100TESTS
About this Product
- SKU:
- RD21767F
- Additional Names:
- Integrin alpha-4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha,CD49d,ITGA4
- Application:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- 9F10
- Clonality:
- Monoclonal
- Conjugate:
- Alexa Fluor® 647
- Extra Details:
- CD49d is a 150 kD A Alpha integrin chain known as A Alpha4 integrin or VLA-4 A Alpha chain. It forms a heterodimer with either integrin B Beta1 (A Alpha4B Beta1, VLA-4) or B Beta7 (A Alpha4B Beta7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. A Alpha4B Beta7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.|This is a AF647 Anti-Human CD49d Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
- Host:
- Mouse
- Isotype:
- IgG1, kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Reddot
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:af647-anti-human-cd49d-antibody-1466.html
