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Antibodies

AF/LE Purified Anti-Mouse CD279/PD-1 Antibody

Product Sizes
50 ug
£178.00
RD21637F-50UG
500 ug
£580.00
RD21637F-500UG
1 mg
£848.00
RD21637F-1MG
About this Product
SKU:
RD21637F
Additional Names:
PD-1, Programmed Death-1
Application:
Block/Inhibit/Neutralise, Flow Cytometry
Buffer:
0.2 uM PBS
translate.label.attr.clone:
29F.1A12
Clonality:
Monoclonal
Concentration:
0.5 mg/ml
Extra Details:
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.|This is a AF/LE Purified Anti-Mouse CD279/PD-1 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rat
Isotype:
IgG2a, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody