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Antibodies

AF488 Anti-Human CD40 Antibody

Product Sizes
20 tests
£152.00
RD20566F-20TESTS
100 tests
£345.00
RD20566F-100TESTS
2 x 100 tests
£493.00
RD20566F-2X100TESTS
About this Product
SKU:
RD20566F
Additional Names:
Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
3A8
Clonality:
Monoclonal
Conjugate:
Alexa Fluor® 488
Extra Details:
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.|This is a AF488 Anti-Human CD40 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Mouse
Isotype:
IgG2a, kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody