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Antibodies

AF488 Anti-Mouse CD54 Antibody

Product Sizes
50 tests
£93.00
RD20350F-50TESTS
100 tests
£127.00
RD20350F-100TESTS
2 x 100 tests
£166.00
RD20350F-2X100TESTS
About this Product
SKU:
RD20350F
Additional Names:
Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1
Application:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
YN1/1.7.4
Clonality:
Monoclonal
Conjugate:
Alexa Fluor® 488
Extra Details:
CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.|This is a AF488 Anti-Mouse CD54 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.
Host:
Rat
Isotype:
IgG2b, kappa
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C Do not freeze. Protect from light.
Supplier:
Reddot
Type:
Antibody: Monoclonal Antibody