anti-Interferon a 2, N27, mouse monoclonal antibody
Product Sizes
100 ug
£432.00
691711-100UG
About this Product
- SKU:
- 691711
- Additional Names:
- Interferon alpha-2, IFN-alpha-2, Interferon alpha-A, LeIF A, IFNA2, IFNA2A, IFNA2B, IFNA2C
- Application:
- ELISA, Immunohistochemistry, Western Blot
- CE/IVD:
- RUO
- translate.label.attr.clone:
- N27
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFN alpha family has over 20 genes and pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFN alpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFN alpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFN alpha are now known and seem to be expressed on most cell types. N27 is specific for human IFN alpha 2 and does not cross react with human IFN alpha 1. N27 reacts with linear peptide 43aa-53aa, placing the epitope outside the immunodominant regions I and II. Positive control: human IFN alpha 2, Namalwa and KGI cells. Pair: N39
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- E. coli derived recombinant human IFN alpha 2c
- Isotype:
- IgG1, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691711
