anti-MHC II DRB, LN-3, mouse monoclonal antibody
Product Sizes
100 ug
£432.00
691708-100UG
About this Product
- SKU:
- 691708
- Application:
- FACS, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- LN-3
- Clonality:
- Monoclonal
- Extra Details:
- MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an A Alpha and B Beta chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. Positive control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Nuclei from pokeweed mitogen-stimulated PBL
- Isotype:
- IgG2b, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691708
