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Antibodies

anti-CD74, LN-2, mouse monoclonal antibody

Product Sizes
100 ug
£432.00
691707-100UG
About this Product
SKU:
691707
Additional Names:
HLA class II histocompatibility antigen gamma chain, HLA-DR antigens-associated invariant chain, Ia antigen-associated invariant chain, Ii, p33, CD antigen CD74 [Cleaved into: Class-II-associated invariant chain peptide, CLIP], CD74, DHLAG
Application:
FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
CE/IVD:
RUO
translate.label.attr.clone:
LN-2
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
LN-2 is directed against the CD74 cluster, established during the IVth Leukocyte Typing Workshops. CD74 comprises four species of proteins (MW 41/35/33 kDa), all coded by a single gene, consisting of nine exons. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. In tissue sections anti CD74 show a binding pattern very similar to that of anti-HLA-DR. It binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. Positive control: Daudi or Raji cells. Tonsil or lymp node.
Formulation:
PBS with 0.02% sodium azide
Host:
Mouse
Immunogen:
Cell extracts from diffuse histiocytic lymphoma SU-DHL-4
Isotype:
IgG1, kappa
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Non-human Primate, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:691707