anti-Plasma Cell Marker, EBS-O-231, mouse monoclonal antibody
Product Sizes
100 ug
£432.00
691670-100UG
About this Product
- SKU:
- 691670
- Application:
- Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EBS-O-231
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- EBS-O-231 recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Positive control: human tonsil.
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Pancreatic cancer related serum mucin
- Isotype:
- IgG2a, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691670
