anti-CD109, EBS-CD-046, mouse monoclonal antibody
Product Sizes
100 ug
£432.00
691614-100UG
About this Product
- SKU:
- 691614
- Additional Names:
- CD109 antigen, 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, Platelet-specific Gov antigen, p180, r150, CD antigen CD109, CD109, CPAMD7
- Application:
- FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EBS-CD-046
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- CD109 is a GPI-anchored member of the alpha-2-macroglobulin (A2M) and complement family of proteins. It is expressed on activated T-cells, platelets, hematopoietic stem cells, megakaryocyte precursors, vascular endothelial cells, basal and myoepithelial cells of secretory glands, and squamous cell carcinomas. A 170-180 kDa precursor is autocatalytically reduced to 150 kDa and 120 kDa forms. On keratinocytes CD109 binds TGF-beta and associates with TGF-beta RI and TGF-beta RII, resulting in inhibition of TGF-beta signalling. Polymorphisms of CD109 include the platelet-specific Gov antigen and the blood group ABH antigens. Alloantibodies directed against these antigens result in unsuccessful platelet transfusions, neonatal alloimmune thrombocytopenia, and post-transfusion purpura. Positive control: human platelets, blood vessels.
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Recombinant human CD109
- Isotype:
- IgG2a, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human, Non-human Primate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691614
