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Antibodies

anti-CD98, IPO-T10, mouse monoclonal antibody

Product Sizes
100 ug
£432.00
691610-100UG
About this Product
SKU:
691610
Additional Names:
4F2 cell-surface antigen heavy chain, 4F2hc, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, CD antigen CD98, SLC3A2, MDU1
Application:
FACS, Immunohistochemistry
CE/IVD:
RUO
translate.label.attr.clone:
IPO-T10
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
CD98 exists as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulphide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intercellular calcium levels and transport L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. Monocytes express high levels of CD98 antigen. Peripheral blood T- and B-cells, as well as NK-cells and granulocytes express low levels of CD98. Activation of T-cells and NK-cells leads to upregulation of CD98. RBCs are negative. IPO-T10 was typed at the VIth International Workshop and Conference on Human Leukocyte Differentiation Antigens. Positive control: Jurkat, MG63, HUT-78, K562, YT, U937 and human lymphocytes or tonsils.
Formulation:
PBS with 0.02% sodium azide
Host:
Mouse
Immunogen:
Stimulated human PBL
Isotype:
IgM, kappa
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:691610