anti-CD61, EBS-CD-034, mouse monoclonal antibody
Product Sizes
100 ug
£432.00
691598-100UG
About this Product
- SKU:
- 691598
- Additional Names:
- Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD antigen CD61, ITGB3, GP3A
- Application:
- FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
- CE/IVD:
- RUO
- translate.label.attr.clone:
- EBS-CD-034
- Clonality:
- Monoclonal
- Concentration:
- 100 ug/ml
- Extra Details:
- EBS-CD-034 reacts with a complex of CD41 and CD61, i.e. alpha IIb integrin and the integrin beta chain. The MW of the GPIIIa is 105 kDa unreduced and 90 kDa reduced. The integrin beta 3 chain can also form a complex called the vitronectin receptor with integrin alpha V: the CD51/CD61 complex. Ligands are fibrinogen, fibronectin, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding. The CD51/CD61 complex is also found on endothelial cells, some B-cells, monocytes/macrophages and tumor cells. Positive control: U937, KG1a, HEL cells, human platelets in lymph nodes or tonsils.
- Formulation:
- PBS with 0.02% sodium azide
- Host:
- Mouse
- Immunogen:
- Stimulated human PBMC's
- Isotype:
- IgM, kappa
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Progen
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:691598
