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Antibodies

anti-CD59, Bra10G, mouse monoclonal antibody

Product Sizes
100 ug
£432.00
691597-100UG
About this Product
SKU:
691597
Additional Names:
CD59 glycoprotein, 1F5 antigen, 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-inhibitory protein, MAC-IP, MEM43 antigen, Membrane attack complex inhibition factor, MACIF, Membrane inhibitor of reactive lysis, MIRL, Protectin, CD antigen CD59, CD59, MIC11, MIN1, MIN2, MIN3, MSK21
Application:
FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
CE/IVD:
RUO
translate.label.attr.clone:
Bra10G
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
CD59, or protectin, is a 18-22 kDa cell surface molecule on a GPI anchor. It regulates complement-mediated cell lysis and is supposed to protect normal and tumor cells from cytotoxic attack by homologous complement through binding to C8 and C9. CD59 is expressed on leukocytes, vascular epithelium, a variety of epithelial cells and placenta. B-cells express low levels. The expression of CD59 on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease Paroxysmal nocturnal hemoglobinuria (PNH). Bra10G was typed at the VIth International Workshop on human leucocyte differentiation antigens. Positive control: Daudi, CEM, K562, HPB-ALL, Jurkat, Raji, human lymphocytes, human lymph node and tonsil.
Formulation:
PBS with 0.02% sodium azide
Host:
Mouse
Immunogen:
K-562 leukemia cells
Isotype:
IgG2b, kappa
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:691597