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Antibodies

anti-CD46, 197-2B1, mouse monoclonal antibody

Product Sizes
100 ug
£432.00
691589-100UG
About this Product
SKU:
691589
Additional Names:
Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD antigen CD46, CD46, MCP, MIC10
Application:
FACS, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
CE/IVD:
RUO
translate.label.attr.clone:
197-2B1
Clonality:
Monoclonal
Concentration:
100 ug/ml
Extra Details:
197-2B1 reacts with human CD46, a 52-58 kDa single chain type 1 transmembrane molecule. CD46 is a cofactor for the factor I regulation of complement components C3b and C4b and contains four N-terminal short consensus repeat (SCR) modules. It is strongly expressed on salivary gland ducts and kidney ducts and often increased on tumor cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria. 197-2B1 has been clustered at the VIth HLDA Workshop. Positive control: K562, U937, HL60, HeLa and Jurkat cells, and human lymphocytes. Lymph node and tonsil.
Formulation:
PBS with 0.02% sodium azide
Host:
Mouse
Immunogen:
Stimulated human leucocytes
Isotype:
IgG2a, kappa
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
Progen
Type:
Antibody: Monoclonal Antibody
  • Manufacturer's Data Sheet:691589